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gSynth®

The gSynth® platform is a proprietary synthesis engine developed to overcome the limitations of accuracy, speed, and scale.  It delivers high-fidelity constructs at the pace required for today’s high-velocity drug discovery.

 

 

Camena Bio

Engineered for performance

Advanced automation

Advanced lab automation

Streamlining the path from digital design to physical construct.  Rapid, consistent output of plates per week. 

Precision design

Precision design

Proprietary design algorithm and enzymatic synthesis for sequence perfect results. 

Manufacturing excellence

Manufacturing excellence

Reliability is the foundation of speed. ISO-certified quality management systems providing operational consistency.


Consistent fidelity

Consistent fidelity

NGS verified and transfection-ready, for immediate downstream use.

 

Camena Bioscience colleague working in the laboratory

A new era of DNA synthesis: next-level innovation

The ability to read, write, and edit DNA is at the heart of the bioengineering biology value chain.

Yet researchers are constrained by existing synthesis technologies, both chemical and enzymatic. Those technologies can be error-prone and have limited ability to produce the DNA sequences you need.

gSynth® has turned that on its head.

Why we're TdT-free Codon optimisation challenges

How it works

Precise de novo
synthesis

Precise de novo synthesis

A plate of generic gSynth reagents are pipetted into wells of a 384 well plate.  After pipetting each well contains a specific mixture of gSynth reagents.

Addamers decapped
and payloads extended

Step 2 no text update Mar 25 900

A proprietary mix of enzymes de-caps Addamers and extends their payloads performing de novo synthesis of DNA sequences. 

Algorithmic assembly
of long DNA molecules

Step 3 text update Mar 25 900 (1)

Addamers are combined to form longer DNA molecules.  Rapid synthesis producing multi-kb per day. 

  • "Our partnership with Camena Bioscience has been outrageously successful."
    Strategic customer
    Top 20 Pharmaceutical company
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The gSynth advantage

  • Universal reagent starting set, compatible with common liquid handlers
  • De novo synthesis of DNA produces any payload
  • A combinatorial and parallel gene assembly approach that accurately and rapidly produces complex DNA sequences  
  • Proprietary design algorithm based on geometric principles and bioinformatics software that can be integrated into existing workflows
  • Produces readily clonable double-stranded DNA 
  • Sequence and supply-chain security
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